If you mean a toothpaste + Vaseline (petroleum jelly) mixture for skin, I’d recommend not using it. There isn’t good evidence that the combination provides meaningful skincare benefits, and toothpaste can irritate or burn skin.
Why people mix them
Online DIY recipes sometimes claim the mixture can:
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Remove dark spots or pigmentation
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Dry out pimples
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Lighten lips or underarms
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Reduce blackheads
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Smooth or brighten skin
These claims aren’t well supported by dermatological evidence.
What each ingredient actually does
Toothpaste
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Contains ingredients designed for teeth, not facial or body skin.
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Some formulas contain fluoride, flavoring agents, detergents, abrasives, or peroxide-related ingredients.
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On skin, these can cause dryness, redness, burning, irritation, or contact dermatitis.
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It may temporarily dry a pimple, but that doesn’t mean it treats acne effectively.
Vaseline (petroleum jelly)
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Acts mainly as an occlusive moisturizer: it forms a protective layer that reduces water loss from the skin.
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It can be useful for dry, cracked skin, lips, and protecting irritated areas.
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It doesn’t bleach skin, remove pigmentation, or dissolve blackheads.
If your goal is a pimple
Instead of toothpaste, a safer DIY-free approach is:
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Gently wash the area.
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Apply a small amount of 2.5% benzoyl peroxide or salicylic acid acne treatment.
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Use a non-comedogenic moisturizer if the skin becomes dry.
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Don’t squeeze or pick the pimple.
If your goal is dry skin
Use plain Vaseline on slightly damp skin. You don’t need toothpaste, and adding it can actually make irritation worse.
If you tell me what you’re trying to treat—pimples, dark spots, dark lips, blackheads, dry skin, or something else—I can give you a safe recipe/routine specifically for that problem.